Deschloroetizolam: A Potent Thienotriazolodiazepine for GABAergic Research

At GlobalChemSolutions.com, we are committed to offering researchers access to high-quality, lab-tested research chemicals. One of the more notable compounds in our benzodiazepine analog catalog is Deschloroetizolam, a potent thienotriazolodiazepine used in central nervous system (CNS) studies and GABA-A receptor modulation research.

Deschloroetizolam is a close analog of Etizolam, sharing many pharmacological properties but with a subtle structural variation that researchers find useful in receptor binding, sedation, anxiolysis, and potency comparison studies.

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What Is Deschloroetizolam?

Deschloroetizolam is a synthetic compound structurally related to Etizolam, except it lacks the chlorine atom on the phenyl ring—hence the prefix “deschloro.” This minor structural change results in slightly altered pharmacodynamics, making it a unique tool for investigating GABA-A receptor modulation and structure-activity relationships (SAR) among thienotriazolodiazepines.

• Chemical Name: 4-(2-methylphenyl)-2-ethyl-9H-thieno[3,2-e][1,2,4]triazolo[4,3-a][1,4]diazepine

• Molecular Formula: C17H17N5S

• Common Forms: Powder, pellet, or solution (for research use only)

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Key Features & Benefits

• ✅ GABA-A Positive Allosteric Modulator (PAM)

• ✅ Structurally Similar to Etizolam

• ✅ Effective in Low Doses (μg to mg range)

• ✅ Supports Anxiolytic and Sedative Research

• ✅ Valuable for SAR and Receptor Affinity Studies

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Why Choose GlobalChemSolutions for Deschloroetizolam?

When you order Deschloroetizolam from GlobalChemSolutions, you receive:

• Verified ≥98% Purity, confirmed by GC-MS and HPLC

• Fast, Worldwide Shipping with secure packaging

• Private, Encrypted Checkout

• Certificate of Analysis (COA) Available

• Expert Customer Support for research-focused inquiries

Our team ensures every batch meets stringent quality standards, offering peace of mind to researchers who rely on chemical integrity and consistency.

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Common Research Applications

⚠️ Deschloroetizolam is strictly intended for scientific research. It is not approved for human or veterinary use.

1. GABA-A Receptor Modulation

Deschloroetizolam enhances GABA-A activity, providing insights into the inhibitory neurotransmission system responsible for relaxation, sedation, and muscle relaxation.

2. Comparative Potency Studies

Researchers compare Deschloroetizolam to Etizolam and other benzodiazepines like Diazepam or Clonazolam to assess potency, duration, and binding profile.

3. Structure-Activity Relationship (SAR) Exploration

By removing the chlorine atom from Etizolam, Deschloroetizolam allows scientists to study how minor structural changes impact receptor affinity and pharmacological action.

4. Forensic and Toxicology Research

Deschloroetizolam is also used in forensic science for identifying and tracking novel psychoactive substances (NPS) in analytical toxicology models.

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Handling & Storage Guidelines

Deschloroetizolam should be stored in a sealed, light-resistant container in a cool, dry location. Exposure to moisture, air, or high temperatures may degrade the compound. Always use appropriate PPE (gloves, goggles, fume hood) when handling.

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Legal Status and Buyer Responsibility

Deschloroetizolam is not for human consumption and is sold only to licensed laboratories and professionals for research purposes. It may be restricted in some jurisdictions. Customers are responsible for understanding and complying with their local laws and regulations.

GlobalChemSolutions does not ship to countries or states where Deschloroetizolam is classified as a controlled substance.

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Conclusion

Deschloroetizolam is a powerful, highly selective thienotriazolodiazepine that offers researchers valuable opportunities to explore GABA-A receptor dynamics, neuropharmacological behavior, and structural effects on potency. Whether used in receptor binding studies or SAR modeling, this compound is a trusted tool in the research community.

Buy Deschloroetizolam today from GlobalChemSolutions.com and experience the highest standards in research chemical sourcing, service, and quality assurance.